lunes, 28 de marzo de 2011

Part A4, Process

4. Meiosis Process
Meiosis is a very specialized process of cell division that produces gametes (eggs and sperm), and is quite distinct from the mitotic cycle of normally dividing cells. In humans, it is estimated that at least 10% of conceptions have defects that probably occurred during meiosis of either paternal or maternal gametes. Most of these will result in miscarriage. Understanding the process of meiosis is therefore fundamental to understanding human health and development. The purpose of meiosis is to reduce the normal diploid cells (2 copies of each chromosome / cell) to haploid cells, called gametes (1 copy of each chromosome per cell). In humans, these special haploid cells resulting from meiosis are eggs (female) or sperm (male). In yeast cells, they are spores.
To carry out this specialized process, the cells duplicate their DNA but follow this by two rounds of division, instead of one. The first division separates the duplicated homologues from each other. This essentially reduces the number of chromosomes in each cell. Thus, we call this the reductional, or Meiosis I division. The second division operates similarly to the mitotic division, and separates the sister chromatids from one another; we call this the equational, or Meiosis II division. The offspring from meiosis have half the number of chromosomes as their parent cell, because they receive just one copy of each chromosome, rather than two. (Compare the offspring in the meiosis diagram to those in mitosis).

http://kentsimmons.uwinnipeg.ca/cm1504/meiosis.htm
http://www-bcf.usc.edu/~forsburg/meiosis.html



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